Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Upper GI Series: Barium Swallow01:24

Upper GI Series: Barium Swallow

The Barium Swallow Study, or a Barium Esophagogram, is a diagnostic imaging method used to visualize the upper gastrointestinal (GI) tract, including the esophagus, stomach, and small intestine. It employs barium sulfate, a radiopaque contrast material, to provide clear images of the upper digestive system, helping to identify abnormalities, diseases, or structural issues.
Purpose and Procedure
Patients undergoing this procedure ingest a liquid containing barium sulfate with a chalky...
Barrett Esophagus-II: Clinical Manifestations and Management01:21

Barrett Esophagus-II: Clinical Manifestations and Management

Individuals with Barrett's esophagus are often asymptomatic, but they may experience symptoms commonly associated with GERD, such as heartburn and acid regurgitation. Additional symptoms can include difficulty swallowing, chest pain, unintentional weight loss, blood in the stool (which may appear black, tarry, or bloody), and episodes of vomiting.
To diagnose Barrett's esophagus, healthcare providers often recommend an endoscopy for those showing symptoms of acid reflux. The procedure entails...
Esophageal Strictures-II: Clinical Features and Management01:26

Esophageal Strictures-II: Clinical Features and Management

Patients with esophageal strictures often experience a range of symptoms. Initially, they may have difficulty swallowing solid foods, which can progress to include liquids. Additional symptoms may involve chest pain or discomfort, regurgitating food and fluids, heartburn, unintentional weight loss, coughing or choking during meals, and hoarseness.
Healthcare providers should gather a comprehensive medical history and conduct a physical examination for diagnosis. If esophageal stricture is...
Barrett Esophagus-I: Introduction01:21

Barrett Esophagus-I: Introduction

Barrett's esophagus is a medical condition where the esophageal mucosa is significantly damaged by stomach acid or other digestive fluids, often due to long-term exposure associated with gastroesophageal reflux disease (GERD). In GERD, a weakened or abnormally relaxed lower esophageal sphincter allows stomach acid to flow persistently into the esophagus.
This constant acid exposure transforms the esophagus's pink mucosal lining (stratified squamous epithelium) into a type of lining more similar...
Endoscopic Procedures I: Esophagogastroduodenoscopy01:29

Endoscopic Procedures I: Esophagogastroduodenoscopy

An Esophagogastroduodenoscopy (EGD) is a diagnostic procedure in which an endoscopist uses a flexible, lighted endoscope to visualize the upper gastrointestinal (GI) tract. The procedure includes visualizing the oropharynx, esophagus, stomach, and the first part of the small intestine, the duodenum.
During an EGD, the endoscope can be used to:
Esophageal Strictures-I: Introduction01:30

Esophageal Strictures-I: Introduction

Esophageal strictures involve abnormal narrowing or tightening of the esophagus. They vary in length and severity, ranging from mild constriction to complete obstruction, and are classified as benign (noncancerous) or malignant (cancerous).
Etiology
The primary cause of esophageal strictures is long-standing gastroesophageal reflux disease (GERD), accounting for about 70 to 80% of adult cases. Chronic acid reflux can lead to injury and scarring of the esophageal lining, culminating in...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The Utilization of the Completeness of Surgery Index in Revision Endoscopic Sinus Surgery Patients on Biologic Therapy for CRSwNP.

International forum of allergy & rhinology·2026
Same author

Systemic Corticosteroids in the Management of Sinonasal Disease: An Evidence-Based Expert Review.

International forum of allergy & rhinology·2026
Same author

Remission in Global Airway Diseases: EUFOREA Consensus Paper.

Allergy·2026
Same author

Novel olfactory cleft computed tomography staging system reveals a trizone anatomic model and biphasic progression in central compartment atopic disease.

The Journal of allergy and clinical immunology·2026
Same author

Paranasal Sinus Squamous Cell Carcinoma and Adenocarcinoma: A SEER Database Analysis.

Cancer medicine·2026
Same author

Delivery of ATSP-7041 by Minimally Invasive Nasal Depot (MIND) to Target Diffuse Intrinsic Pontine Glioma.

Molecular cancer therapeutics·2026

Related Experiment Video

Updated: Jul 9, 2026

Adapting Human Videofluoroscopic Swallow Study Methods to Detect and Characterize Dysphagia in Murine Disease Models
08:32

Adapting Human Videofluoroscopic Swallow Study Methods to Detect and Characterize Dysphagia in Murine Disease Models

Published on: March 1, 2015

Dysphagia after chemoradiation: analysis by modified barium swallow.

Benjamin S Bleier1, Marc S Levine, Rosemarie Mick

  • 1Department of Otorhinolaryngology-Head and Neck Surgery, University of Pennsylvania, Philadelphia, USA.

The Annals of Otology, Rhinology, and Laryngology
|December 14, 2007
PubMed
Summary

Chemoradiation for head and neck cancer significantly impairs swallowing, leading to pneumonia and feeding tube dependence in many patients. Modified barium swallow studies reveal these deglutition issues.

Related Experiment Videos

Last Updated: Jul 9, 2026

Adapting Human Videofluoroscopic Swallow Study Methods to Detect and Characterize Dysphagia in Murine Disease Models
08:32

Adapting Human Videofluoroscopic Swallow Study Methods to Detect and Characterize Dysphagia in Murine Disease Models

Published on: March 1, 2015

Area of Science:

  • Otolaryngology
  • Oncology
  • Radiology

Background:

  • Chemoradiation is a standard treatment for head and neck cancer.
  • Dysphagia is a common complication following chemoradiation.
  • Modified barium swallow (MBS) studies are used to assess swallowing function.

Purpose of the Study:

  • To describe MBS findings in head and neck cancer patients post-chemoradiation.
  • To correlate MBS findings with clinical outcomes like pneumonia and gastrostomy tube dependence.

Main Methods:

  • Retrospective review of 49 patients with head and neck cancer.
  • Patients underwent MBS for dysphagia after chemoradiation.
  • Clinical data including pneumonia and gastrostomy tube status were analyzed.

Main Results:

  • Nonlaryngeal lesions correlated with increased cricopharyngeal impairment (p = .04).
  • Concomitant chemotherapy increased epiglottic changes versus radiotherapy alone (p = .05).
  • 31.9% developed pneumonia; 79.6% required long-term gastrostomy tubes (mean 18.1 months).

Conclusions:

  • Chemoradiation negatively impacts swallowing at multiple levels.
  • A significant proportion of patients experience pneumonia and feeding tube dependence.
  • MBS findings correlate with clinical variables, highlighting treatment sequelae.