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High density lipoprotein subfractions and physical activity: changes after moderate and heavy exercise training
J Fernández-Pardo1, J Rubiés-Prat, J Pedro-Botet
1Departamento de Medicina, Hospital General, Universidad de Murcia, Spain.
Summary
Heavy intensity physical training significantly increased HDL-cholesterol, HDL2-cholesterol, and apoprotein A-I in healthy men. Moderate intensity training also improved these markers, but to a lesser extent.
Area of Science:
- Exercise Physiology
- Cardiovascular Health
- Lipid Metabolism
Background:
- High density lipoprotein (HDL) subfractions play a crucial role in cardiovascular health.
- Understanding the impact of different exercise intensities on HDL subfractions is important for public health.
- Previous research has shown exercise can influence lipid profiles, but specific effects on HDL subfractions require further investigation.
Purpose of the Study:
- To investigate the effects of two months of heavy versus moderate intensity physical training on HDL subfractions in young healthy men.
- To compare the changes in HDL-cholesterol, HDL2-cholesterol, apoprotein A-I, and HDL subfraction ratios between the two training groups.
Main Methods:
- 106 healthy young men participated in a two-month physical training program.
- Subjects were divided into a Heavy Intensity Training Program (HITP) group (n=40) and a Moderate Intensity Training Program (MITP) group (n=66).
- Energy expenditure was estimated daily for both groups, and changes in body fat, HDL-cholesterol, HDL2-cholesterol, and apoprotein A-I were measured.
Main Results:
- The HITP group showed a reduction in body fat and significant increases in HDL-cholesterol (8.4%), HDL2-cholesterol (30%), and apoprotein A-I (16.9%).
- The MITP group did not show changes in body fat but had increases in HDL-cholesterol (5.6%), HDL2-cholesterol (17.1%), and apoprotein A-I (5.6%).
- The increase in apoprotein A-I was significantly greater in the HITP group, and the apo A-I/A-II ratio increased in both groups, indicating a shift towards HDL2 subfractions.
Conclusions:
- Heavy intensity physical training is more effective than moderate intensity training in improving HDL subfractions and reducing body fat in young healthy men.
- Both training programs positively influence HDL metabolism, particularly increasing the cardioprotective HDL2 subfraction.
- These findings highlight the importance of exercise intensity in modulating lipid profiles for cardiovascular health benefits.