Related Experiment Video

Updated: Jul 8, 2026

Quantitative Examination of Antibiotic Susceptibility of Neisseria gonorrhoeae Aggregates Using ATP-utilization Commercial Assays and Live/Dead Staining
08:04

Quantitative Examination of Antibiotic Susceptibility of Neisseria gonorrhoeae Aggregates Using ATP-utilization Commercial Assays and Live/Dead Staining

Published on: February 8, 2019

Gonococcal infections in newborns and in adolescents

Noni MacDonald1, Tim Mailman, Shalini Desai

  • 1Dalhousie University, Division Pediatric Infectious Diseases, IWK Health Center, Halifax, Nova Scotia, Canada. noni.macdonald@dal.ca

Advances in Experimental Medicine and Biology
|January 16, 2008
PubMed

Insights

Gonococcal infections in newborns are rare in developed nations but persist in developing countries. Early diagnosis and treatment are crucial for newborns, mothers, and partners to prevent serious health issues.

Area of Science:

  • Public Health
  • Infectious Diseases
  • Pediatrics

Background:

  • Gonococcal infections in newborns, while uncommon in industrialized nations, pose a significant threat in developing countries due to high maternal infection rates.
  • Untreated gonococcal infections in newborns can lead to severe, long-term health complications.

Purpose of the Study:

  • To highlight the ongoing challenges of gonococcal infections in newborns and adolescents.
  • To emphasize the importance of prompt diagnosis and comprehensive treatment strategies.

Main Methods:

  • Review of current epidemiological data on gonococcal infections.
  • Analysis of treatment and prevention strategies for newborns, adolescents, and their sexual partners.

Main Results:

  • Adolescents are identified as a key demographic driving the persistent epidemic of gonorrhea in industrialized countries.
  • Effective management requires not only newborn treatment but also investigation and treatment of the mother and her partner(s).

Conclusions:

  • Substantial changes in sexual behavior, coupled with enhanced education and youth-friendly sexual health services, are essential to curb the adolescent gonorrhea epidemic.
  • Access to comprehensive sexual transmitted infection (STI) care and education is a fundamental right for adolescents.

More Related Videos

A Murine Model of Group B Streptococcus Vaginal Colonization10:19

A Murine Model of Group B Streptococcus Vaginal Colonization

Published on: November 16, 2016

A Neonatal Imaging Model of Gram-Negative Bacterial Sepsis08:46

A Neonatal Imaging Model of Gram-Negative Bacterial Sepsis

Published on: August 12, 2020

Related Concept Videos

Sexually Transmitted Infections01:26

Sexually Transmitted Infections

Sexually transmitted infections (STIs) are diseases transmitted primarily through unsafe sexual interactions. Bacteria, viruses, or parasites cause them and can result in severe health complications if untreated.ChlamydiaThe bacterium Chlamydia trachomatis is responsible for the disease Chlamydia, the most common STI in the United States. This peculiar pathogen requires human cells to reproduce, residing intracellularly. The initial infection often goes unnoticed because it typically does not...
Cryptococcal Meningitis01:27

Cryptococcal Meningitis

Cryptococcal meningitis is a life-threatening opportunistic infection predominantly associated with HIV/AIDS, accounting for over 100,000 deaths annually worldwide. However, it also affects individuals with other forms of immunosuppression, including those undergoing immunosuppressive therapy, organ transplant recipients, patients with innate immunodeficiencies, and individuals with hematological disorders. The infection is caused mainly by Cryptococcus neoformans and Cryptococcus gattii,...
Streptococcal Pharyngitis01:27

Streptococcal Pharyngitis

Streptococcal pharyngitis, commonly known as “strep throat,” is an acute infection of the oropharyngeal tissues caused by the Gram‑positive Group A Streptococcus (Streptococcus pyogenes). Transmission occurs primarily through respiratory droplets expelled during coughing, sneezing, or talking.Mechanisms of Host Entry and Immune EvasionUpon entering the host, S. pyogenes adheres to the mucosal epithelial cells of the pharynx via surface proteins, notably lipoteichoic acid and the antiphagocytic...
Acne Infection01:27

Acne Infection

Acne is a multifactorial skin condition primarily affecting adolescents and young adults, with a global prevalence estimated to exceed 75% in this demographic. The condition is characterized by the formation of comedones (blackheads and whiteheads), papules, pustules, nodules, and, in severe cases, cysts, particularly in areas rich in sebaceous glands such as the face, neck, chest, and back. The pathogenesis involves increased sebum production, follicular hyperkeratinization, colonization by...
Bacterial Meningitis I: Introduction01:22

Bacterial Meningitis I: Introduction

Bacterial meningitis is a severe, life-threatening inflammation of the meninges, particularly the pia mater and arachnoid mater, affecting the subarachnoid space, ventricles, and cerebrospinal fluid (CSF). If untreated, it can lead to significant neurological complications or death.Causative AgentsCommon pathogens vary with age and immune status. In adults, major organisms include Streptococcus pneumoniae, Neisseria meningitidis, and Haemophilus influenzae. Streptococcus agalactiae (group B...
Bacterial Meningitis01:24

Bacterial Meningitis

Bacterial meningitis is a severe infectious disease involving inflammation of the meninges, the protective membranes surrounding the brain and spinal cord. It occurs when pathogenic bacteria cross the blood–brain barrier and enter the cerebrospinal fluid. Common causative organisms include Neisseria meningitidis, Streptococcus pneumoniae, Haemophilus influenzae type b, Listeria monocytogenes, and Escherichia coli K1. The exact route of entry varies by pathogen and host condition.Routes of Entry...