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Related Concept Videos

Open Angle Glaucoma: Treatment01:27

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In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
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Related Experiment Video

Updated: Jul 8, 2026

Intravitreal Injections in the Ovine Eye
03:37

Intravitreal Injections in the Ovine Eye

Published on: July 5, 2022

Intravitreal pharmacotherapy: applications in retinal disease.

Anita G Prasad1, Ramin Schadlu, Rajendra S Apte

  • 1Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, St. Louis, MO 63110, USA.

Comprehensive Ophthalmology Update
|January 19, 2008
PubMed
Summary

Intravitreal pharmacotherapies are increasingly used for retinal diseases like diabetic macular edema. While effective, potential complications such as cataracts and glaucoma require careful management and monitoring.

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Area of Science:

  • Ophthalmology
  • Retinal Diseases
  • Pharmacotherapy

Background:

  • Intravitreal pharmacotherapies are frequently employed for various retinal conditions.
  • Indications span choroidal neovascularization, diabetic macular edema, and neoplastic processes.

Purpose of the Study:

  • To review current and emerging intravitreal pharmacotherapies for retinal diseases.
  • To discuss the benefits and complications associated with these treatments.
  • To guide practitioners in maximizing therapeutic benefits while minimizing ocular and systemic risks.

Main Methods:

  • Review of current literature on intravitreal pharmacotherapies.
  • Analysis of indications, efficacy, and complications.
  • Discussion of new pharmacologic agents and systemic medication applications.

Main Results:

  • Intravitreal injections are indicated for a range of retinal diseases.
  • Common complications include cataract formation, glaucoma, and endophthalmitis.
  • New agents and systemic drug applications expand treatment possibilities.

Conclusions:

  • Intravitreal pharmacotherapy offers expanded treatment options for retinal diseases.
  • Careful consideration of benefits versus risks, including potential complications, is essential.
  • Emerging data will refine therapeutic strategies for optimal patient outcomes.