[Prevention of prosthesis infections]
Related Experiment Video
Updated: Jul 8, 2026

A Periprosthetic Joint Candida albicans Infection Model in Mouse
Published on: February 2, 2024
Peter Holmberg Jørgensen1, Kirill Gromov, Kjeld Søballe
1Arhus Universitetshospital, Arhus Sygehus, Ortopaedkirurgisk Afdeling, Tumor-infektionssektoren, Arhus C. phjor@as.aaa.dk
Abstract:
Prosthetic infection is a feared complication to surgery with alloplastics and has a high degree of comorbidity. Prophylaxis is concentrated on commonly-accepted hygienic behaviour, optimization of the patient's general health status, peri-operative antibiotics (one dose before surgery and three doses during the first 24 hours postoperatively) and antibiotic loaded cement. Laminary flow reduces the risk of prosthesis infection but there is no clear evidence of any effect to concomitant antibiotic prophylaxis.
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