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Updated: Jul 7, 2026

Solid Lipid Nanoparticles (SLNs) for Intracellular Targeting Applications
Published on: November 17, 2015
[Preparation and characterization of solid lipid nanoparticles of norcantharidin]
1Faculty of Pharmaceutical Science, Shandong University, Jinan 250012, China.
Objective:
To prepare and characterize the solid lipid nanoparticles containing norcantharidin.
Methods:
Entrapment efficiency was studied to choose the best method of preparing norcantharidin solid lipid nanoparticles. The physico-chemical properties of norcantharidin solid lipid nanoparticles were investigated.
Results:
The entrapment efficiency of norcantharidin in solid lipid nanoparticles was 54.6%, the average particle diameter was 190 nm, and it was stable at 4 degrees C for 3 months.
Conclusion:
Solid lipid nanoparticles of norcantharidin prepared has high entrapment efficiency and good stability.

