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Updated: Jul 7, 2026
04:40
Venous Thrombosis Assay in a Mouse Model of Cancer
Published on: January 5, 2024
[Cancer in patients with venous thromboembolic disease]
J M Calvo Romero1, E M Lima Rodríguez
1Servicio de Medicina Interna. Hospital Ciudad de Coria, Coria, Cáceres, Spain. jmcalvo@orangemail.es
Anales De Medicina Interna (Madrid, Spain : 1984)
|February 19, 2008
Summary
Nearly one-fifth of patients with venous thromboembolic disease (VTD) also had cancer, often an adenocarcinoma. Cancer significantly increases adverse events in VTD patients, indicating a poor prognosis.
Area of Science:
- Medical research
- Oncology
- Hematology
Context:
- Venous thromboembolic disease (VTD) is a significant health concern.
- Cancer is a known risk factor for VTD.
- Understanding the interplay between VTD and cancer is crucial for patient management.
Purpose:
- To investigate the characteristics of patients presenting with venous thromboembolic disease (VTD) and co-existing cancer in a specific geographic region.
- To determine the frequency of cancer in VTD patients and vice versa.
- To assess the impact of cancer on VTD prognosis and adverse events.
Summary:
- A prospective observational study identified 94 VTD patients in a rural area between 2002 and 2005.
- 18.1% of VTD patients had cancer, predominantly adenocarcinoma with distant metastases.
- Cancer patients experienced significantly higher rates of adverse events (death, hemorrhage, recurrence) compared to non-cancer VTD patients (64.7% vs. 9.1%).
Impact:
- The findings highlight a substantial co-occurrence of cancer in VTD patients.
- Cancer diagnosis in VTD patients is associated with a poorer prognosis and increased adverse events.
- This study underscores the importance of considering cancer in VTD patients and vice versa for improved clinical outcomes.
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