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Genovefa Kolovou1, Katherine Anagnostopoulou, Dimitri P Mikhailidis

  • 1Onassis Cardiac Surgery Center, 356 Sygrou Ave 176 74 Athens, Greece. genovefa@kolovou.com

Current Pharmaceutical Design
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To learn more about the function of a gene, researchers can observe what happens when the gene is inactivated or “knocked out,” by creating genetically engineered knockout animals. Knockout mice have been particularly useful as models for human diseases such as cancer, Parkinson’s disease, and diabetes.