Related Experiment Video
Updated: Feb 13, 2026

07:37
An Adoptive Transfer Model of Rheumatoid Arthritis in Mice
Published on: June 6, 2025
1.2K
Thumb carpal metacarpal arthritis
Ann E Van Heest1, Patricia Kallemeier
1Department of Orthopaedic Surgery, University of Minnesota, Minneapolis 55454, USA.
Summary
Thumb carpometacarpal (CMC) osteoarthritis is common, especially in older women. Treatment ranges from conservative therapies to surgical options like trapeziectomy and ligament reconstruction.
Area of Science:
- Orthopedics
- Hand Surgery
- Rheumatology
Background:
- The thumb carpometacarpal (CMC) joint is a frequent site for surgical reconstruction due to osteoarthritis.
- Radiographic prevalence of thumb CMC osteoarthritis is 25% in men and 40% in women over 75.
- Ligamentous support is crucial for thumb CMC joint stability.
Purpose of the Study:
- To provide an overview of thumb carpometacarpal (CMC) osteoarthritis.
- To discuss diagnostic criteria and classification systems.
- To outline current non-surgical and surgical treatment modalities.
Main Methods:
- Diagnosis relies on physical examination (pain, tenderness, instability) and radiographic evaluation.
- Disease severity is classified using the four-stage Eaton system.
- Treatment strategies are determined by the extent of arthritic involvement.
Main Results:
- Thumb CMC osteoarthritis affects a significant portion of the elderly population, particularly women.
- The Eaton classification system provides a reproducible method for assessing disease severity.
- A variety of non-surgical and surgical interventions are available.
Conclusions:
- Thumb CMC osteoarthritis is a prevalent condition requiring comprehensive management.
- Accurate diagnosis and staging are essential for effective treatment planning.
- Treatment options are diverse, ranging from conservative measures to complex surgical reconstructions.

