The link between IL-23 and Th17 cell-mediated immune pathologies.

Mandy J McGeachy1, Daniel J Cua

  • 1Schering-Plough Biopharma (Formerly DNAX Research), 901 California Avenue, Palo Alto, CA 94304, United States. mandy.mcgeachy@spcorp.com

Summary

Interleukin-23 (IL-23) and T helper 17 (Th17) cells are key in autoimmune inflammation. This review explores Th17 cell discovery, regulation, and the complex roles of IL-23 in disease.

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