Related Experiment Video
Updated: Jul 6, 2026

Isolating Human Peripheral Blood Mononuclear Cells and CD4+ T cells from Sézary Syndrome Patients for Transcriptomic Profiling
Published on: October 14, 2021
[The history of lymphoma classifications with special consideration of cutaneous lymphomas]
C Niermann1, H J Schulze, C Hallermann
1Fachklinik Hornheide, Münster.
Abstract:
For modern evidence-based medicine, classification systems are necessary to guarantee a uniform approach for therapy and for estimating prognosis. The comparability of clinical studies and international communication require a common language and are only possible with modern international classification systems. But because all classifications are artificial, they only mirror the current state of knowledge and may change dramatically over decades. This review discusses the history of lymphoma classifications systems with a special focus on the topic of primary cutaneous lymphomas, emphasizing special problems in terminology.
Related Concept Videos
Lymphoid Cells and Tissues
Lymphoid cells consist of various types of immune system cells. These include B and T lymphocytes, which are responsible for producing antibodies and killing infected cells, respectively. Dendritic cells act as messengers between the innate and adaptive...
Skin Cancer
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Primary Lymphoid Organs
The red bone marrow is a soft, spongy tissue nestled in the interior of long bones such as the humerus and femur. It is the site...
Development of the Lymphatic System
The first lymph sacs to form are the paired jugular lymph sacs located at the junction of the internal jugular and subclavian veins. From these sacs, lymphatic capillary plexuses extend to the thorax, upper limbs, neck, and head, eventually forming lymphatic vessels. Each jugular lymph sac maintains a...
Secondary Lymphoid Organs
The spleen is a vital organ in the lymphatic system, nestled in the upper left side of the abdomen. It is composed of two primary regions: the red pulp and the white pulp, each having distinct functions. The red pulp performs a significant role in blood filtration. It efficiently purges the blood of old or damaged red blood cells and...
Skin Diseases and Disorders
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
