Related Experiment Video
Updated: Jul 5, 2026

Use of Viral Entry Assays and Molecular Docking Analysis for the Identification of Antiviral Candidates against Coxsackievirus A16
Published on: July 15, 2019
[Acute transverse myelitis associated with coxsackievirus B---A retrospective analysis of 7 patients]
Zhan-dong Liu1, De-xin Wang, Zi-jing Feng
1Department of Neurology, Beijing Friendship Hospital Affiliated to Capital Medical University, Beijing 100050 China.
Objective:
Acute Transverse myelitis (ATM) is a focal inflammatory disorder of the spinal cord, resulting in motor, sensory, and autonomic nerve dysfunction. There is often a clearly defined rostral border of sensory dysfunction. Nowadays, the pathogenesis of ATM is not clear. The present study aimed to understand possible relationship between ATM and infection with Coxsackievirus B.
Methods:
IgM antibody against Coxsackievirus B was detected in cerebrospinal fluid of 33 patients with ATM.
Results:
In 7 of the 33 cases with ATM, the IgM andtibody Coxsackievirus B (CVB) was positive. No infections with other pathogens were found at the onset of the disease.
Conclusion:
The pathogenesis of ATM may involve infection with Coxsackievirus B.
Related Concept Videos
Viral Meningitis
Poliomyelitis
Cytomegalovirus Disease
Arboviral Encephalitis
Cryptococcal Meningitis
Endocarditis II: Clinical Features of Infective Endocarditis