Related Experiment Video
Updated: Jul 5, 2026
09:51
Investigating Protein Sequence-structure-dynamics Relationships with Bio3D-web
Published on: July 16, 2017
Installing a local copy of the Reactome Web site and database.
1EMBL-European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK.
Current Protocols in Bioinformatics
|April 23, 2008
Summary
Reactome provides an open-source biological pathway database, curated by experts and freely available online. Its data and software can be downloaded for local installation, enabling flexible data analysis and custom additions.
Area of Science:
- Bioinformatics
- Molecular Biology
- Systems Biology
Background:
- Biological pathways are crucial for understanding cellular functions.
- Existing pathway databases may have limitations in accessibility or customizability.
Purpose of the Study:
- To introduce the Reactome project and its comprehensive biological pathway database.
- To highlight the open-source nature and accessibility of Reactome resources.
Main Methods:
- Curating pathway information from domain experts.
- Peer-reviewing and editorial processes for data validation.
- Developing open-source software and a publicly accessible website.
Main Results:
- Reactome offers a robust database of curated biological pathways.
- The project provides open-source software and freely downloadable data.
- The Reactome website (http://www.reactome.org) serves as a central access point.
Conclusions:
- Reactome promotes open science by providing freely accessible and downloadable pathway data.
- The open-source model allows for flexible data interrogation and local installation.
- Users can extend the database with their own information, fostering collaborative research.
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