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Updated: Jul 5, 2026

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A Mouse Model of Vascularized Heterotopic Spleen Transplantation for Studying Spleen Cell Biology and Transplant Immunity
Published on: June 11, 2019
Survival surgery: removal of the spleen or thymus
J P Reeves1, P A Reeves1, L Thomas Chin2
1Food and Drug Administration, Bethesda, Maryland.
Current Protocols in Immunology
|April 25, 2008
Abstract:
Although for most experiments lymphoid tissue is removed from the freshly sacrificed animal, there are several circumstances which require the surgical removal, under anesthesia, of either the thymus or spleen, and the recovery of the animal for further investigation. This unit describes survival surgery for removal of the adult spleen as well as the adult and neonatal thymus of the mouse.
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