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Related Concept Videos

Disorders of the Male Reproductive System01:20

Disorders of the Male Reproductive System

Men's health issues are increasingly recognized as significant, with several conditions posing common threats. Among these, testicular cancer is especially prevalent in younger men, particularly those aged 20 to 35 years. The disease often manifests as a painless mass in the testicles, sometimes accompanied by a sensation of heaviness or a dull ache.
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra. Symptoms...

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Related Experiment Video

Updated: Jul 5, 2026

Microarray-based Identification of Individual HERV Loci Expression: Application to Biomarker Discovery in Prostate Cancer
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Microarray-based Identification of Individual HERV Loci Expression: Application to Biomarker Discovery in Prostate Cancer

Published on: November 2, 2013

Serum selenium level and prostate cancer: a case-control study.

Gholamreza Pourmand1, Sepehr Salem, Kamran Moradi

  • 1Urology Research Center, Sina Hospital, Medical Sciences/University of Tehran, Tehran, Iran.

Nutrition and Cancer
|April 30, 2008
PubMed
Summary
This summary is machine-generated.

Lower serum selenium levels are linked to a higher risk of prostate cancer. This finding supports selenium

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Sequencing Small Non-coding RNA from Formalin-fixed Tissues and Serum-derived Exosomes from Castration-resistant Prostate Cancer Patients
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Sequencing Small Non-coding RNA from Formalin-fixed Tissues and Serum-derived Exosomes from Castration-resistant Prostate Cancer Patients

Published on: November 19, 2019

Related Experiment Videos

Last Updated: Jul 5, 2026

Microarray-based Identification of Individual HERV Loci Expression: Application to Biomarker Discovery in Prostate Cancer
13:19

Microarray-based Identification of Individual HERV Loci Expression: Application to Biomarker Discovery in Prostate Cancer

Published on: November 2, 2013

Sequencing Small Non-coding RNA from Formalin-fixed Tissues and Serum-derived Exosomes from Castration-resistant Prostate Cancer Patients
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Sequencing Small Non-coding RNA from Formalin-fixed Tissues and Serum-derived Exosomes from Castration-resistant Prostate Cancer Patients

Published on: November 19, 2019

Area of Science:

  • Oncology
  • Nutritional Biochemistry

Background:

  • Prostate cancer is a significant health concern globally.
  • Selenium is investigated for its potential chemopreventive properties against cancer.

Purpose of the Study:

  • To compare serum selenium levels in prostate cancer patients versus controls.
  • To assess the association between serum selenium and prostate cancer risk.

Main Methods:

  • Prospective case-control study involving 62 prostate cancer patients and 68 controls.
  • Serum selenium levels measured using Zeeman graphite furnace atomic absorption spectrometry.
  • Statistical analysis adjusted for age, BMI, and smoking status.

Main Results:

  • Mean serum selenium was significantly lower in prostate cancer cases (66.3 μg/l) than controls (77.5 μg/l).
  • Serum selenium showed an inverse association with prostate cancer risk (OR=0.16 for highest vs. lowest tertile).
  • No correlation found between serum selenium and age, BMI, or PSA levels.

Conclusions:

  • Lower serum selenium levels are associated with an increased risk of prostate cancer.
  • These findings support the hypothesis that selenium may offer protection against prostate cancer development.