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Updated: Jul 5, 2026

Isolation, Transfection, and Culture of Primary Human Monocytes
Published on: December 16, 2019
Insights into cellular microRNAs and human immunodeficiency virus type 1 (HIV-1)
1Department of Biochemistry and Molecular Biology, George Washington University School of Medicine, Washington, District of Columbia, USA.
Abstract:
Recent findings suggest that mammalian microRNAs (miRNAs) may influence viral replication in host cells. Studies on HIV-1 infection have contributed in part to the development of this notion. Herein, we review, in brief, some of the evidence supportive of an interplay between human miRNAs and HIV-1 in cells. Several cellular miRNAs potentially act to restrict HIV-1 replication, and the virus has countermeasures to evade such restriction.
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