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Updated: Jul 5, 2026
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Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential
Published on: May 25, 2020
Detection of visual field progression in glaucoma.
M Kovalska1, M C Grieshaber, A Schötzau
1University Eye Clinic, Basel, Switzerland.
Klinische Monatsblatter Fur Augenheilkunde
|May 6, 2008
Summary
Event analysis detected more glaucoma progression than trend analysis. Trend analysis also required more data to confirm visual field loss progression in glaucoma patients.
Area of Science:
- Ophthalmology
- Medical Statistics
Background:
- Glaucoma is a leading cause of irreversible blindness.
- Early detection of glaucomatous visual field loss progression is crucial for timely intervention.
- Current analytical methods for detecting progression vary in sensitivity and timing.
Purpose of the Study:
- To compare the efficacy of event analysis versus trend analysis in detecting glaucomatous visual field loss progression.
- To evaluate the timing and number of examinations required by each method to identify progression.
Main Methods:
- A comparative study analyzing visual field data from glaucoma patients.
- Baseline established using the average of the second and third examinations.
- Event analysis based on the Collaborative Normal Tension Glaucoma Study method.
- Trend analysis utilizing point-wise linear regression.
Main Results:
- Out of 251 glaucoma patients, data from 235 left eyes and 225 right eyes were analyzed.
- Event analysis identified 44 progressing series, while point-wise regression identified only 14.
- Concordant progression was found in 9 eyes; trend analysis required additional fields in 7 of these to confirm progression.
Conclusions:
- Point-wise linear regression analysis is less sensitive in detecting glaucoma progression compared to event analysis.
- Trend analysis, using point-wise linear regression, identifies progression later than event analysis.
- Event analysis appears more effective for earlier detection of visual field loss progression in glaucoma.
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