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Updated: Jul 5, 2026

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Published on: April 25, 2011
Pathology of the optic nerve.
Hans Rolf Jäger1, Katherine Anne Miszkiel
1Lysholm Department of Neuroradiology, The National Hospital for Neurology and Neurosurgery, 8-11 Queen Square, London WC1 3BG, United Kingdom. r.jager@ion.ucl.ac.uk
This article reviews optic nerve and chiasm pathologies. It covers diseases affecting the optic nerve/sheath complex but excludes posterior visual pathway conditions.
Area of Science:
- Ophthalmology
- Neurology
Background:
- The optic nerve, optic nerve/sheath complex, and chiasm are critical components of the visual system.
- Pathologic processes affecting these structures can lead to significant visual impairment.
Purpose of the Study:
- To provide a comprehensive overview of pathologic processes affecting the optic nerve, optic nerve/sheath complex, and chiasm.
- To differentiate these conditions from pathologies of the posterior visual pathways.
Main Methods:
- Review of existing literature on optic nerve and chiasm pathology.
- Discussion of key pathologic entities and their clinical manifestations.
Main Results:
- Detailed examination of various optic neuropathies and chiasmal pathologies.
- Emphasis on conditions directly impacting the optic nerve and its surrounding sheath, as well as the optic chiasm.
Conclusions:
- Understanding optic nerve and chiasm pathology is essential for accurate diagnosis and management of visual dysfunction.
- This review serves as a focused resource for clinicians and researchers interested in these specific neuro-ophthalmic conditions.
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