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Updated: Feb 16, 2026

A Mouse Model of Ankle-Subtalar Complex Joint Instability
Published on: October 28, 2022
Sensorimotor deficits with ankle sprains and chronic ankle instability
1Department of Human Services, University of Virginia, Exercise and Sport Injury Lab, 202 Emmet Street South, Charlottesville, VA 22904-4407, USA. jhertel@virginia.edu
Patients with ankle instability experience sensorimotor deficits affecting conscious perception and motor control. Both feedback and feedforward mechanisms are altered, impacting ankle function and stability.
Area of Science:
- Biomechanics
- Neuroscience
- Sports Medicine
Background:
- Sensorimotor deficits are a known issue in patients with ankle sprains and chronic ankle instability.
- Research has identified potential physiological explanations for these deficits over several decades.
Purpose of the Study:
- To elucidate the physiological explanations for sensorimotor deficits in chronic ankle instability.
- To understand the specific alterations in conscious perception, reflex responses, and motor control.
Main Methods:
- Analysis of sensorimotor measures in patients with ankle instability.
- Review of existing research literature on ankle instability and sensorimotor control.
Main Results:
- Alterations in conscious perception of somatosensory information are evident.
- Deficits in reflex responses and efferent motor control are present.
- Both feedback and feedforward motor control mechanisms are demonstrably altered.
Conclusions:
- Sensorimotor deficits, including altered perception and motor control, are characteristic of ankle instability.
- The precise origin of these deficits (ligamentous, spinal, or supraspinal) requires further investigation.
- Altered feedback and feedforward mechanisms are key components of motor control deficits in ankle instability.
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