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Updated: Jul 4, 2026
18:50
Microsurgical Clip Obliteration of Middle Cerebral Aneurysm Using Intraoperative Flow Assessment
Published on: September 25, 2009
Orbitofrontal syndrome after a cerebral aneurysm operation. A case report
A Frías Ibáñez1, A Malea Fernández, M Dorado García
1Psychiatry Department, Hospital Universitario La Fe, Valencia, Spain. alvarofrias66@hotmail.com
Actas Espanolas De Psiquiatria
|June 5, 2008
Summary
Orbitofrontal syndrome, characterized by cognitive and affective changes, can result from brain injury. Psychotherapy and medication effectively manage symptoms and improve patient outcomes.
Area of Science:
- Neuroscience
- Psychiatry
- Clinical Psychology
Background:
- Orbitofrontal syndrome is an organic mental disorder affecting cognitive, affective, and inhibitory cerebral mechanisms.
- It involves damage to the orbitofrontal system's structures and connections.
Observation:
- A 19-year-old woman experienced significant personality changes and behavioral alterations for one year post-middle cerebral artery aneurysm operation.
- The patient exhibited serious behavioral alterations.
Findings:
- Drug treatment led to a marked reduction in psychopathology intensity.
- Psychotherapy proved beneficial in improving family management and addressing metacognitive deficits.
Implications:
- The overlap between orbitofrontal syndrome and psychiatric disorders offers insights into the biological basis of mental illness.
- Behavioral techniques, particularly psychotherapy, are recommended treatments due to metacognitive deficits and environmental dependency.
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