Related Experiment Video
Updated: Jul 4, 2026

Gastric Mucosa Quantitative Polymerase Chain Reaction Analysis for Detecting Helicobacter pylori and Antibiotic Resistance
Published on: March 7, 2025
New strategies for Helicobacter pylori eradication
Michael Selgrad1, Peter Malfertheiner
1Department of Gastroenterology, Hepatology and Infectious Diseases, Otto-von-Guericke University Magdeburg, Magdeburg, Germany.
Abstract:
Helicobacter pylori infection is highly prevalent worldwide and is a major cause of diseases occurring in the upper gastrointestinal tract. Successful eradication therapy improves H. pylori-related symptoms in functional dyspepsia, cures peptic ulcer disease and may prevent gastric cancer. During the past decade, the success rate of recommended eradication regimens declined from over 90% to about 80%, a critical threshold for effectiveness of the therapy according to the current guidelines. This is mainly because of the rising antimicrobial resistance and underlines that it is imperative to develop new treatment approaches. The prevention of the initial infection by a suitable vaccination might be the new therapeutic strategy for the future.
More Related Videos
06:40Quantitative Polymerase Chain Reaction (qPCR)-Based Rapid Diagnosis of Helicobacter pylori Infection and Antibiotic Resistance
Published on: July 28, 2023
04:56Detection of Helicobacter pylori Infection and Antibiotic Resistance via Stool Quantitative Polymerase Chain Reaction Analysis
Published on: May 16, 2025
Related Concept Videos
Treating Helicobacter pylori in Peptic Ulcers: Antimicrobial Therapy
Peptic Ulcer Disease IV: Management
The therapeutic approach involves ensuring adequate rest, implementing drug therapy, promoting smoking cessation, making dietary modifications, and emphasizing long-term follow-up care.
Pharmacological management
The prevailing therapy for peptic ulcers involves a combination of managing the patient's current medication...
Acid Suppressive Drugs for Peptic Ulcer Disease: Proton Pump Inhibitors
Gastric acid, a potent cocktail of hydrogen and chloride ions, is produced in specialized parietal cells within the...
Peptic Ulcer Disease II: Pathophysiology
Gastritis II: Pathophysiology
Gastritis III: Clinical Manifestations and Management
Clinical manifestations of acute gastritis
The patient with acute gastritis may have a rapid onset of symptoms, such as epigastric pain or discomfort, dyspepsia, anorexia, hiccups, or nausea and vomiting, which can last from a few hours to a few days. Erosive or hemorrhagic gastritis may cause bleeding, which may manifest as blood in vomit or as...