Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Neuron Structure

Neuron Structure

Neurons are the main type of cell in the nervous system that generate and transmit electrochemical signals. They primarily communicate with each other using neurotransmitters at specific junctions called synapses. Neurons come in many shapes that often relate to their function, but most share three main structures: an axon and dendrites that extend out from a cell body.
Structure and Function of Neurons
The neuronal cell body—the soma— houses the nucleus and organelles vital to cellular...

Neurogenesis and Regeneration of Nervous Tissue

Neurogenesis and Regeneration of Nervous Tissue

In the CNS, neurogenesis, the birth of new neurons from stem cells, is limited to the hippocampus in adults. In other regions of the brain and spinal cord, neurogenesis is almost non-existent due to inhibitory influences from neuroglia, especially oligodendrocytes, and the absence of growth-stimulating cues. The myelin produced by oligodendrocytes in the CNS inhibits neuronal regeneration. Furthermore, astrocytes proliferate rapidly after neuronal damage, forming scar tissue that physically...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Sex Differences in Characteristics and Outcomes Among Patients With Hypertrophic Cardiomyopathy: Insights From the REVEAL-HCM Study.

Journal of the American Heart Association·2026

Same author

Integrated interpretation of exercise electrocardiography and cardiopulmonary exercise testing for detection of significant coronary artery stenosis.

Journal of cardiology·2026

Same author

Comprehensive Assessment of the KDM2B-Associated Neurodevelopmental Disorder and the 12q24.31 Microdeletion Syndrome.

Clinical genetics·2026

Same author

Chorea-acanthocytosis presenting with epilepsy at onset harboring novel compound heterozygous <i>VPS13A</i> mutations.

Clinical parkinsonism & related disorders·2026

Same author

Giant Pancreatic Acinar Cell Carcinoma: A Case Report and Review of Molecular Pathogenesis and Emerging Therapies.

Cureus·2026

Same author

Colon Cancer Presenting as an Incarcerated Incisional Hernia: A Case Report.

Cureus·2026

Same journal

[Neuropathological Autopsies in Japan: Current Scenario and Challenges].

Brain and nerve = Shinkei kenkyu no shinpo·2026

Same journal

[Telemedicine and Digital Technologies in Neurological Intractable Diseases].

Brain and nerve = Shinkei kenkyu no shinpo·2026

Same journal

[Disaster Countermeasures for Intractable Neurological Disease].

Brain and nerve = Shinkei kenkyu no shinpo·2026

Same journal

[Supporting Health Care Transition for Patients with Childhood-Onset Chronic Conditions: Within Intractable Disease Care in Japan].

Brain and nerve = Shinkei kenkyu no shinpo·2026

Same journal

[Multidisciplinary Collaboration between Hospitals and Clinics at the University Hospital and the Core Hospital for the Treatment of Intractable Diseases].

Brain and nerve = Shinkei kenkyu no shinpo·2026

Same journal

[The Role of Coordinators for Intractable Diseases in Japan].

Brain and nerve = Shinkei kenkyu no shinpo·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Jul 4, 2026

Widespread Transduction of Mouse Neocortical Neurons by Subarachnoid Injection of AAV2

Widespread Transduction of Mouse Neocortical Neurons by Subarachnoid Injection of AAV2

Published on: May 23, 2025

[Neuroacanthocytosis update].

Mio Ichiba¹, Masayuki Nakamura, Akira Sano

¹Department of Psychiatry, Kagoshima University Graduate School of Medical and Dental Sciences, 8-35-1 Sakuragaoka, Kagoshima 890-8544, Japan.

Brain and Nerve = Shinkei Kenkyu No Shinpo

|June 24, 2008

Summary

This summary is machine-generated.

Neuroacanthocytosis encompasses genetic disorders linking neurological issues with abnormal red blood cells. Molecular genetics advances help differentiate these complex conditions, improving diagnosis and understanding.

More Related Videos

A Novel Strategy Combining Array-CGH, Whole-exome Sequencing and In Utero Electroporation in Rodents to Identify Causative Genes for Brain Malformations

A Novel Strategy Combining Array-CGH, Whole-exome Sequencing and In Utero Electroporation in Rodents to Identify Causative Genes for Brain Malformations

Published on: December 1, 2017

Related Experiment Videos

Last Updated: Jul 4, 2026

Widespread Transduction of Mouse Neocortical Neurons by Subarachnoid Injection of AAV2

Widespread Transduction of Mouse Neocortical Neurons by Subarachnoid Injection of AAV2

Published on: May 23, 2025

A Novel Strategy Combining Array-CGH, Whole-exome Sequencing and In Utero Electroporation in Rodents to Identify Causative Genes for Brain Malformations

A Novel Strategy Combining Array-CGH, Whole-exome Sequencing and In Utero Electroporation in Rodents to Identify Causative Genes for Brain Malformations

Published on: December 1, 2017

Area of Science:

Neurogenetics
Hematology
Clinical Neurology

Context:

Neuroacanthocytosis is a group of rare, genetically diverse disorders.
Characterized by neurological deficits and acanthocytosis (abnormal red blood cells).
Historically classified based on clinical presentation, including movement disorders.

Purpose:

To provide an overview of neuroacanthocytosis syndromes.
To highlight the role of molecular genetics in classifying these disorders.
To differentiate between core neuroacanthocytosis syndromes and those involving lipoprotein abnormalities.

Summary:

Neuroacanthocytosis syndromes are classified into two main groups: core syndromes (e.g., chorea-acanthocytosis, McLeod syndrome) affecting the basal ganglia and causing movement disorders, and those associated with lipoprotein disorders (e.g., abetalipoproteinemia) leading to ataxia and neuropathy.
Rare conditions like Huntington's disease-like 2 and pantothenate kinase-associated neurodegeneration (PKAN), including HARP syndrome, are also discussed within the core group.
The second group, involving abetalipoproteinemia and hypobetalipoproteinemia, presents with fat malabsorption, spinocerebellar ataxia, peripheral neuropathy, and retinitis pigmentosa, but typically lacks prominent movement disorders.

Impact:

Molecular genetics has significantly improved the ability to distinguish between different neuroacanthocytosis subtypes.
Enhanced understanding aids in accurate diagnosis and potential therapeutic strategies.
Facilitates research into the specific genetic underpinnings and pathogenic mechanisms of these rare diseases.