[Middle-molecular peptides in blood as endogenous regulators of lipid peroxidation in the normal state and during...

Influence of middle mass peptides upon red blood cell membrane lipid peroxidation was studied in the cells irradiated by ultraviolet in vitro as well as content of the lipid peroxidation products was estimated in mice tissues after intravenous administration of the peptide fraction. Dissimilar effects of the middle mass peptides in vivo and in vitro and role of these peptides in regulation of lipid peroxidation under conditions of burns are discussed. Negative correlation was found between content of middle mass peptides and products of lipid peroxidation in healthy volunteers.