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Cervical ectopic pregnancy successfully treated with local methotrexate injection.
Isabel Cerveira1, Cristina Costa, Fernando Santos
1Departments of Obstetrics, Hospital de São Teotónio, Viseu, Portugal. isabelcerveira@hotmail.com
Fertility and Sterility
|July 1, 2008
Summary
Intra-amniotic methotrexate successfully terminated a cervical ectopic pregnancy resistant to intramuscular treatment. This method offers a safe alternative for specific cases, prioritizing patient stability.
Area of Science:
- Reproductive Medicine
- Maternal-Fetal Medicine
- Gynecologic Oncology
Background:
- Cervical ectopic pregnancy is a rare but potentially life-threatening condition.
- Systemic methotrexate (MTX) is a common treatment, but resistance can occur.
- Alternative treatment strategies are crucial for managing resistant cases.
Observation:
- A case of cervical ectopic pregnancy resistant to intramuscular MTX was reported.
- Intra-amniotic MTX injection under ultrasonographic guidance was administered.
- The patient was a 31-year-old woman with early cervical pregnancy.
Findings:
- Successful pregnancy termination was achieved with intra-amniotic MTX.
- The procedure was performed without complications or adverse side effects.
- This highlights the efficacy of localized MTX administration.
Implications:
- Intra-amniotic MTX is a potentially effective and safe treatment for cervical ectopic pregnancy.
- Treatment choice should consider gestational age, fertility preservation, and hemodynamic stability.
- This approach may be valuable in cases of MTX resistance.
