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Periorbital changes associated with topical bimatoprost
Theodoros Filippopoulos1, Jayter S Paula, Nurhan Torun
1Department of Ophthalmology, Glaucoma Consultation Service, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts 02114, USA.
Ophthalmic Plastic and Reconstructive Surgery
|July 23, 2008
Summary
Daily bimatoprost 0.03% eye drops can cause noticeable periorbital changes, including fat loss and eyelid alterations. These effects may be reversible upon discontinuing the glaucoma medication.
Area of Science:
- Ophthalmology
- Dermatology
Background:
- Glaucoma management often involves topical medications.
- Bimatoprost is a prostaglandin analog commonly used for lowering intraocular pressure.
Observation:
- Chronic daily use of bimatoprost 0.03% was investigated in glaucoma patients.
- Periorbital changes were observed in treated eyes compared to untreated fellow eyes.
Findings:
- Topical bimatoprost induced periorbital fat atrophy, deepened upper eyelid sulcus, and reduced lower eyelid fullness.
- Involution of dermatochalasis and relative enophthalmos were also noted.
- Changes were confirmed as unilateral, not present before treatment, and partially reversible after discontinuation.
Implications:
- Healthcare providers and patients should be aware of potential cosmetic side effects of bimatoprost.
- Understanding these changes is crucial for managing patient expectations and treatment adherence.
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