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[Effect of baclofen on characteristics of the cellular immune response]

I N Tiurenkov, M A Samotrueva, A N Ovcharova

    Eksperimental'Naia I Klinicheskaia Farmakologiia
    |July 26, 2008
    PubMed

    It has been established that GABA-B receptor agonist baclofen restores the cellular parts (the delay-type hypersensitivity reaction index, thymus weight, and thymocyte number) of immunogenesis under the experimental suppression conditions. This is probably caused both by the direct influence of baclofen on the receptors of immunocompetent cells and by the normalization of the nervous regulation of the immune response.

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