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Updated: Jul 2, 2026

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Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas
Published on: January 17, 2018
[Endoscopic surgery in sinonasal inverted papillomas]
Gang Wang1, Lei Chen, Rongguang Wang
1Department of Otolaryngology-Head and Neck Surgery, Chinese PLA General Hospital, Beijing 100853, China.
Summary
Endoscopic resection is a safe and effective treatment for sinonasal inverted papillomas, offering minimally invasive surgery. Thorough tumor removal and regular follow-up are crucial for successful outcomes in patients.
Area of Science:
- Otolaryngology
- Surgical Oncology
Background:
- Sinonasal inverted papillomas are benign tumors with a high recurrence rate and potential for malignant transformation.
- Traditional surgical approaches can be associated with significant morbidity.
Purpose of the Study:
- To evaluate the efficacy and clinical value of transnasal endoscopic resection for sinonasal inverted papillomas.
- To assess the outcomes and recurrence rates associated with this minimally invasive technique.
Main Methods:
- A retrospective analysis of 40 patients who underwent transnasal endoscopic resection for sinonasal inverted papillomas between July 1999 and April 2005.
- Tumor staging was performed according to the Krouse classification.
Main Results:
- Complete lesion removal was achieved in all patients.
- The recurrence rate was 15% (6/40) over a mean follow-up of 45.1 months.
- Malignant transformation occurred in 7.5% (3/40) of cases, with no reported mortality.
Conclusions:
- Transnasal endoscopic resection is a safe and effective minimally invasive treatment for sinonasal inverted papillomas.
- Complete tumor excision and consistent post-operative surveillance are essential for optimal patient management and preventing recurrence.
