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Remifentanil-propofol versus fentanyl-propofol for monitored anesthesia care during hysteroscopy
Jung-Hee Ryu1, Jae-Hun Kim1, Kum-Suk Park1
1Department of Anesthesiology and Pain Medicine, Seoul National University College of Medicine, Seoul, South Korea; Department of Anesthesiology and Pain Medicine, Seoul National University Hospital, Seoul, South Korea.
Study Objective:
To compare the efficacy of remifentanil-propofol with that of fentanyl-propofol for monitored anesthesia care during hysteroscopy.
Design:
Prospective, randomized study.
Setting:
Operating room and postanesthesia care unit of a university hospital.
Patients:
30 ASA physical status I and II adult patients undergoing hysteroscopic procedures.
Interventions:
After propofol infusion, patients received a bolus of remifentanil (group R, 0.5 microg/kg) or fentanyl (group F, 1 microg/kg) 4 minutes before starting the procedure and then received a continuous infusion of remifentanil (group R, 0.05 microg/kg per min) or bolus doses of fentanyl (group F, 0.5 microg/kg).
Measurements And Main Results:
Patients in group R had lower pain scores than patients in group F (0-0 vs 0-7, P < 0.05) and more stable blood pressures (74 +/- 15 vs 85 +/- 9 mmHg, P < 0.05) one minute after the start of the procedure. However, no differences were observed in other variables (recovery profiles and satisfaction scores).
Conclusion:
Remifentanil seems to be a safe and effective analgesic adjunct for monitored anesthesia care of hysteroscopic surgery.
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