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Chemoselective Modification of Viral Surfaces via Bioorthogonal Click Chemistry
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Published on: August 19, 2012

Sensitive DNA probe for photochemical ligation prepared in click chemistry

Takehiro Ami1, Hiroshi Matsumura, Kenzo Fujimoto

  • 1Innovation Plaza Ishikawa, JST, 1-1 Asahidai, Nomi, Ishikawa 923-1292, Japan.

Nucleic Acids Symposium Series (2004)
|September 9, 2008
PubMed

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In situ hybridization (ISH) is a technique used to detect and localize specific DNA or RNA molecules in cells, tissue, or tissue sections using a labeled probe. The technique was first used in 1969 for the investigation of nucleic acids. It is currently an essential tool in scientific research and clinical settings, especially for diagnostic purposes.
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