Related Experiment Video
Updated: Jul 1, 2026

Applying an Inducible Expression System to Study Interference of Bacterial Virulence Factors with Intracellular Signaling
Published on: June 25, 2015
Introduction to bacterial signal transduction networks
1Department of Bioscience, Graduate School of Agriculture, Kinki University, 3327 204 Nakamachi, Nara 631-8505, Japan.
Abstract:
Transcriptional analysis using a DNA microarray is an extremely efficient method for analyzing two-component signal transduction networks. Here we introduce three such networks in Escherichia coli that were clarified using a DNA microarray: a PhoQ/PhoP system that senses extracellular Mg2+ and controls the gene expression for adaptation to environmental Mg2+ deprivation (Mg2+ stimulon); an EvgS/EvgA signal transduction system that activates expression of multiple drug efflux pumps and acid resistance genes; and a signal transduction cascade between EvgS/EvgA and PhoQ/PhoP.
More Related Videos
Related Concept Videos
Bacterial Signaling
Signal Transduction: Overview
Typically, signal transduction involves three...
Global Regulatory Systems
Bacterial Translocation and Protein Secretion
Gene Regulation in Microbial Communities: Quorum Sensing
Intracellular Signaling Cascades

