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Updated: Jun 30, 2026
05:39
Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus
Published on: May 16, 2025
[Reticular erythematous plaques]
Summary
Reticular erythematous mucinosis (REM) syndrome, common in young women, presents with skin lesions on the chest and back. It is often linked to lupus erythematosus tumidus and effectively treated with hydroxychloroquine, topical tacrolimus, or pulsed dye laser therapy.
Area of Science:
- Dermatology
- Autoimmune Diseases
Background:
- Reticular erythematous mucinosis (REM) syndrome is a rare skin condition.
- It primarily affects young women, presenting with characteristic skin lesions.
Observation:
- REM syndrome lesions typically manifest on the chest and upper back.
- The condition is diagnosed via clinical presentation and histological examination.
- A frequent association exists between REM syndrome and lupus erythematosus tumidus.
Findings:
- Both REM syndrome and associated lupus erythematosus tumidus show positive responses to chloroquine treatment.
- Alternative therapies including topical tacrolimus and pulsed dye laser are effective.
- These alternative treatments offer a favorable side effect profile.
Implications:
- Early diagnosis and treatment of REM syndrome can improve patient outcomes.
- Understanding the association with lupus erythematosus tumidus aids in comprehensive patient management.
- Exploring novel therapeutic options like topical tacrolimus and laser therapy expands treatment possibilities for REM syndrome.
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