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Related Experiment Videos

Intravoxel incoherent motion imaging using spin echoes.

D Le Bihan1, R Turner

  • 1Diagnostic Radiology Department, Warren G. Magnuson Clinical Center, National Institutes of Health, Bethesda, Maryland 20892.

Magnetic Resonance in Medicine
|June 1, 1991
PubMed
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This review covers spin echo diffusion measurements and their combination with MR imaging for creating diffusion coefficient maps. It also explores extending these techniques to intravoxel incoherent motion (IVIM) imaging, including blood microcirculation.

Area of Science:

  • Magnetic Resonance Imaging
  • Biophysics
  • Medical Physics

Background:

  • Diffusion measurement is a key application of Magnetic Resonance (MR) techniques.
  • Understanding water molecule diffusion provides insights into tissue microstructure.
  • Spin echo sequences are fundamental for diffusion-weighted imaging.

Purpose of the Study:

  • To review the fundamental principles of diffusion measurement using spin echo sequences.
  • To explain the integration of diffusion principles with MR imaging for diffusion coefficient mapping.
  • To discuss the extension of diffusion imaging to intravoxel incoherent motions (IVIM), including blood flow.

Main Methods:

  • Review of established spin echo pulse sequences for diffusion encoding.
  • Principles of combining diffusion gradients with MR imaging acquisition.

Related Experiment Videos

  • Methodologies for analyzing intravoxel incoherent motions (IVIM).

    • Main Results:

    • Spin echo sequences enable quantitative measurement of diffusion coefficients.
    • MR imaging combined with diffusion principles generates spatially resolved diffusion maps.
    • IVIM imaging extends beyond simple diffusion to include complex motions like microcirculation.

    Conclusions:

    • Spin echo diffusion measurements are foundational for advanced MR imaging applications.
    • Diffusion coefficient mapping offers valuable diagnostic information.
    • IVIM imaging presents technical challenges but holds significant potential for understanding tissue perfusion and microcirculation.