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A phase-sensitive method of flip angle mapping.

Glen R Morrell1

  • 1Radiology Department, University of Utah, Salt Lake City, Utah 84108-1218, USA. glen.morrell@hsc.utah.edu

Magnetic Resonance in Medicine
|September 26, 2008
PubMed
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A new radiofrequency (RF) excitation method encodes flip angle in phase, enabling precise B1 mapping. This phase-sensitive technique expands the measurable flip angle range compared to conventional double-angle methods.

Area of Science:

  • Magnetic Resonance Imaging
  • Radiofrequency Pulse Design

Background:

  • Accurate B1 field mapping is crucial for quantitative MRI.
  • Conventional double-angle techniques have limitations in measuring a wide range of flip angles.

Purpose of the Study:

  • To present a novel phase-sensitive radiofrequency excitation scheme for B1 mapping.
  • To demonstrate its capability for three-dimensional flip angle mapping.

Main Methods:

  • Developed a phase-sensitive RF excitation scheme using nonselective hard pulses.
  • Encoded flip angle information within the phase of the excitation.
  • Integrated the scheme with gradient recalled echo (GRE) and echo-planar (EP) readouts.
  • Acquired 3D flip angle maps.

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Main Results:

  • The phase-sensitive method allows for flip angle measurements over a significantly wider range than double-angle methods.
  • Imaging time is comparable to conventional 3D double-angle techniques.
  • Phantom and in vivo studies validated the method's performance.

Conclusions:

  • The presented phase-sensitive B1 mapping technique offers improved accuracy and range over conventional methods.
  • It is compatible with various fast imaging sequences, making it clinically relevant.