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Updated: Jun 30, 2026
06:51
A Minimally Invasive Model of Aortic Stenosis in Swine
Published on: October 20, 2023
Aortic stenosis: diagnosis and treatment
Brian H Grimard1, Jan M Larson
1Mayo Clinic, St. Augustine, FL 32086, USA. grimard.brian@mayo.edu
American Family Physician
|September 30, 2008
Summary
Aortic stenosis, a common heart valve disease, requires aortic valve replacement for symptomatic patients. Asymptomatic individuals with aortic stenosis can often be monitored with watchful waiting and regular echocardiography.
Area of Science:
- Cardiology
- Valvular Heart Disease
- Geriatric Cardiology
Background:
- Aortic stenosis is a prevalent cardiac valve disease in developed nations, impacting 3% of individuals over 65.
- While asymptomatic patients have a similar survival rate to controls, symptomatic patients without intervention face a 2-3 year survival.
- Compensatory mechanisms like left ventricular hypertrophy fail as aortic stenosis progresses, leading to heart failure, angina, or syncope.
Purpose of the Study:
- To outline management strategies for aortic stenosis based on symptom status and disease severity.
- To emphasize the importance of echocardiography in diagnosing and monitoring aortic stenosis.
- To highlight the need for patient education and management of concurrent cardiac conditions.
Main Methods:
- Review of current clinical guidelines and evidence for aortic stenosis management.
- Utilizing Doppler echocardiography for disease severity assessment and monitoring.
- Clinical assessment of symptoms and left ventricular function.
Main Results:
- Aortic valve replacement is recommended for symptomatic patients with significant aortic stenosis confirmed by echocardiography.
- Watchful waiting is appropriate for most asymptomatic patients, even with hemodynamically significant disease.
- Serial echocardiography is advised based on stenosis severity: annually for severe, 1-2 years for moderate, 3-5 years for mild.
Conclusions:
- Management of aortic stenosis hinges on symptom presentation and echocardiographic findings.
- Prompt medical attention for new symptoms is crucial for patients with aortic stenosis.
- Comprehensive management includes addressing comorbidities like hypertension and coronary artery disease.
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