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Related Concept Videos

Skin Cancer01:30

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Abnormal Proliferation02:23

Abnormal Proliferation

Under normal conditions, most adult cells remain in a non-proliferative state unless stimulated by internal or external factors to replace lost cells. Abnormal cell proliferation is a condition in which the cell's growth exceeds and is uncoordinated with normal cells. In such situations, cell division persists in the same excessive manner even after cessation of the stimuli, leading to persistent tumors. The tumor arises from the damaged cells that replicate to pass the damage to the daughter...
Abnormal Proliferation02:23

Abnormal Proliferation

Under normal conditions, most adult cells remain in a non-proliferative state unless stimulated by internal or external factors to replace lost cells. Abnormal cell proliferation is a condition in which the cell's growth exceeds and is uncoordinated with normal cells. In such situations, cell division persists in the same excessive manner even after cessation of the stimuli, leading to persistent tumors. The tumor arises from the damaged cells that replicate to pass the damage to the daughter...
Atypical Pneumonia01:14

Atypical Pneumonia

Atypical pneumonia, often caused by Mycoplasma pneumoniae, is a form of pulmonary infection that differs from the classical presentation of bacterial pneumonia in both its cause and clinical symptoms. Mycoplasma pneumoniae is a pleomorphic bacterium notable for its lack of a rigid cell wall. This structural characteristic imparts resistance to beta-lactam antibiotics and significantly influences the bacterium’s behavior within the human host.Other pathogens responsible for the disease include...
Loss of Tumor Suppressor Gene Functions01:12

Loss of Tumor Suppressor Gene Functions

Tumor suppressor genes are normal genes that can slow down cell division, repair DNA mistakes, or program the cells for apoptosis in case of irreparable damage. Hence, they play an essential role in preventing the proliferation of damaged cells.
When the tumor suppressor genes develop mutations or are lost, cells start growing out of control, leading to cancer. However, a single functional copy of the tumor suppressor gene is enough for the cells to maintain their normal functions and cell...
Cancers Originate from Somatic Mutations in a Single Cell02:21

Cancers Originate from Somatic Mutations in a Single Cell

Cancer arises from mutations in the critical genes that allow healthy cells to escape cell cycle regulation and acquire the ability to proliferate indefinitely. Though originating from a single mutation event in one of the originator cells, cancer progresses when the mutant cell lines continue to gain more and more mutations, and finally, become malignant. For example, chronic myelogenous leukemia (CML) develops initially as a non-lethal increase in white blood cells, which progressively...

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Related Experiment Video

Updated: Jun 30, 2026

Microsatellite DNA Genotyping and Flow Cytometry Ploidy Analyses of Formalin-fixed Paraffin-embedded Hydatidiform Molar Tissues
11:54

Microsatellite DNA Genotyping and Flow Cytometry Ploidy Analyses of Formalin-fixed Paraffin-embedded Hydatidiform Molar Tissues

Published on: October 20, 2019

Atypical moles.

Peggy R Cyr1

  • 1Maine Medical Center Family Medicine Residency Program, Portland, ME, USA. cyrp@mmc.org

American Family Physician
|September 30, 2008
PubMed
Summary
This summary is machine-generated.

Atypical moles, identified by specific visual cues, require regular skin monitoring and sun avoidance. Early detection and removal of concerning moles can mitigate melanoma risk.

More Related Videos

Cell Population Analyses During Skin Carcinogenesis
06:53

Cell Population Analyses During Skin Carcinogenesis

Published on: August 21, 2013

Related Experiment Videos

Last Updated: Jun 30, 2026

Microsatellite DNA Genotyping and Flow Cytometry Ploidy Analyses of Formalin-fixed Paraffin-embedded Hydatidiform Molar Tissues
11:54

Microsatellite DNA Genotyping and Flow Cytometry Ploidy Analyses of Formalin-fixed Paraffin-embedded Hydatidiform Molar Tissues

Published on: October 20, 2019

Cell Population Analyses During Skin Carcinogenesis
06:53

Cell Population Analyses During Skin Carcinogenesis

Published on: August 21, 2013

Area of Science:

  • Dermatology
  • Oncology
  • Preventive Medicine

Background:

  • Atypical moles (nevi) present distinct visual characteristics.
  • Multiple atypical moles increase melanoma risk, particularly in familial atypical mole and melanoma syndrome.
  • Regular monitoring and appropriate management are crucial for patients with atypical moles.

Purpose of the Study:

  • To outline the clinical identification and management of atypical moles.
  • To emphasize the importance of monitoring for melanoma risk.
  • To provide guidance on when and how to remove atypical moles.

Main Methods:

  • Visual identification of atypical moles based on size (>6 mm), color variegation, indistinct borders, and texture.
  • Recommendations for patient counseling including sun avoidance, family screening, and annual skin checks.
  • Utilizing total body photography and dermoscopy for monitoring mole changes and new lesions.

Main Results:

  • Atypical moles exhibit specific clinical features.
  • The number of atypical moles and family history are significant risk factors for melanoma.
  • Surgical excision is indicated for atypical moles showing signs of malignant transformation.

Conclusions:

  • Patients with atypical moles need regular monitoring and counseling on risk factors.
  • Total body photography and dermoscopy are valuable tools for surveillance.
  • Selective removal of atypical moles with concerning features is recommended over prophylactic removal of all atypical moles.