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Updated: Jun 29, 2026
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Pre-Chiasmatic, Single Injection of Autologous Blood to Induce Experimental Subarachnoid Hemorrhage in a Rat Model
Published on: June 18, 2021
Reversible cerebral vasoconstriction syndrome presenting with haemorrhage
Ernestina Santos1, Yuening Zhang, Alastair Wilkins
1University of Bristol Institute of Clinical Neurosciences, Department of Neurology, Frenchay Hospital, Bristol, UK.
Journal of the Neurological Sciences
|October 7, 2008
Summary
Reversible cerebral vasoconstriction syndromes (RCVS) can cause intracranial hemorrhage. Recognizing this presentation is key for diagnosing RCVS, a condition often overlooked.
Area of Science:
- Neurology
- Neuroimaging
- Vascular Neurology
Background:
- Reversible cerebral vasoconstriction syndromes (RCVS) are defined by temporary narrowing of brain arteries, often causing thunderclap headaches.
- Differentiating RCVS from primary central nervous system vasculitis is crucial for appropriate patient management.
- The clinical spectrum of RCVS is still being defined, necessitating expanded diagnostic criteria.
Observation:
- Intracranial hemorrhage is an under-recognized clinical feature of RCVS.
- Four patient cases illustrate RCVS presenting with intracranial hemorrhage.
- These cases highlight the importance of considering hemorrhage in the RCVS diagnostic workup.
Findings:
- Intracranial hemorrhage can be a presenting sign of RCVS.
- The presence of hemorrhage broadens the known clinical presentation of RCVS.
- This finding aids in the recognition and diagnosis of RCVS.
Implications:
- Enhanced recognition of RCVS-associated intracranial hemorrhage can improve diagnostic accuracy.
- Understanding this association may lead to earlier and more effective treatment strategies for RCVS.
- Further research is warranted to elucidate the mechanisms and frequency of intracranial hemorrhage in RCVS.
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