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Complementary therapies, herbs, and other OTC agents.
1Memorial Sloan-Kettering Cancer Center, New York, New York, USA.
Oncology (Williston Park, N.Y.)
|October 22, 2008
Summary
Graviola shows anticancer properties in lab studies, but human trials are lacking. Websites promote it for cancer, yet no safety or effectiveness evidence exists in people.
Area of Science:
- Phytochemistry
- Pharmacology
- Oncology
Background:
- Graviola (Annona muricata) is a tropical fruit with a history of traditional use.
- In vitro studies suggest graviola possesses anticancer properties.
- There is a lack of clinical evidence regarding graviola's effects in humans.
Purpose of the Study:
- To evaluate the current evidence for graviola's use in cancer treatment.
- To highlight the discrepancy between in vitro findings and human data.
- To emphasize the need for caution in promoting graviola for cancer.
Main Methods:
- Review of existing in vitro and traditional use data.
- Assessment of human clinical trial availability.
- Analysis of online claims regarding graviola and cancer.
Main Results:
- Graviola extracts demonstrated cytotoxic effects against cancer cells in laboratory settings.
- No human studies have investigated the safety or efficacy of graviola for cancer.
- Numerous websites promote graviola for cancer patients, citing limited evidence.
Conclusions:
- Graviola's anticancer potential is suggested by in vitro research but remains unproven in humans.
- Promoting graviola for cancer treatment without human data is not supported by scientific evidence.
- Further clinical research is essential to determine graviola's safety and efficacy in cancer patients.
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