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Updated: Jun 28, 2026

Morphological and Compositional Analysis of Neutrophil Extracellular Traps Induced by Microbial and Chemical Stimuli
Published on: November 4, 2022
[Interaction of neutrophils and different bacterial agents]
Abstract:
Neutrophils migrate on the epithelial surface and interact with microflora of mucous membrane, then activate, realize their effect or functions and destroyed as a result of necrosis or apoptosis. We determined the influence of Staphylococcus aureus, Escherichia coli, Lactobacillus spp. and Bifidobacterium spp. on viability of neutrophils. It was revealed that influence of different bacterial factors on the process of neutrophils' apoptosis is not equal: resident bacteria of women genital tract mucous membrane (Lactobacillus spp. and Bifidobacterium spp.) have powerful apoptogenic effect on neutrophils, unlike the facultative microorganisms (S. aureus and E. coli) which have lesser activity.
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