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Using Digital Image Correlation to Characterize Local Strains on Vascular Tissue Specimens
Published on: January 24, 2016
Compression-induced damage and internal tissue strains are related.
K K Ceelen1, A Stekelenburg, S Loerakker
1Department of Biomedical Engineering, Eindhoven University of Technology, P.O. Box 513, Building W-hoog 4.11, 5600 MB Eindhoven, The Netherlands. karlienk@gmail.com
Journal of Biomechanics
|November 18, 2008
Summary
Tissue deformation, specifically maximum shear strain, is a key factor in pressure-related deep tissue injury. This finding suggests muscle deformation can serve as a reliable indicator for predicting tissue damage.
Area of Science:
- Biomedical Engineering
- Tissue Mechanics
- Wound Healing Research
Background:
- Pressure-related deep tissue injury (DTI) is a severe wound type with poor healing outcomes.
- Current understanding of DTI pathogenesis is limited, hindering prevention and early detection.
- Ischaemia was traditionally considered the primary cause, but tissue deformation is emerging as a significant factor.
Purpose of the Study:
- To evaluate strain parameters as predictive indicators for pressure-induced deep tissue injury.
- To investigate the role of tissue deformation in the aetiology of DTI.
- To establish a reliable method for predicting DTI using mechanical properties.
Main Methods:
- A combined animal-experimental and numerical approach was employed.
- Various strain parameters were analyzed for their correlation with tissue damage.
- Finite element modeling was utilized to reduce biological variation and refine predictive indicators.
Main Results:
- A reproducible, monotonic increase in damage was observed with increasing maximum shear strain above a specific threshold.
- This relationship between maximum shear strain and damage was consistent across multiple experiments, indicating an intrinsic muscle property.
- Tissue deformation was confirmed as a critical factor in DTI development.
Conclusions:
- Maximum shear strain can serve as a generic predictive indicator for pressure-related deep tissue injury.
- Muscle deformation plays a significant role in the aetiology of DTI.
- Finite element modeling enhances the reliability of predicting DTI based on muscle deformation.
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