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Updated: Jun 27, 2026

Handwriting Analysis Indicates Spontaneous Dyskinesias in Neuroleptic Naïve Adolescents at High Risk for Psychosis
Published on: November 21, 2013
[Phases of psychosis]
Merete Nordentoft1, Mette Bertelsen, Lone Petersen
1Psykiatrisk Center, Bispebjerg Hospital, DK-2400 København NV. mn@dadlnet.dk
Schizophrenia development involves distinct phases, with early indicators including cognitive and social deficits. Outcomes vary, with recovery, remission, institutional care, or chronic psychosis affecting individuals post-episode.
Area of Science:
- Neuroscience and Psychiatry
- Developmental Psychology
Context:
- Schizophrenia and psychosis are complex mental health conditions with a multi-phase developmental trajectory.
- Longitudinal and birth cohort studies provide critical insights into early indicators and long-term outcomes.
Purpose:
- To elucidate the developmental phases of psychosis, particularly schizophrenia.
- To identify early markers and understand the diverse long-term outcomes following psychotic episodes.
Summary:
- Individuals who develop schizophrenia often exhibit pre-existing lower cognitive and social functioning, impaired neuromotor development, and emotional difficulties.
- Post-psychotic episode outcomes are varied: approximately 20% achieve full recovery, 25% experience remission without full recovery, 15% require institutional care, and 40% remain chronically psychotic.
Impact:
- Highlights the importance of early detection and intervention for individuals at high risk of schizophrenia.
- Informs prognostic models and treatment strategies by detailing the spectrum of recovery and chronicity in psychosis.
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