Related Experiment Video
Updated: Jun 27, 2026

07:23
Light-induced Patterning and Grafting for Slippery Surfaces based on Silane-coated Nanoporous Structures
Published on: November 14, 2025
Photoreactive coating for high-contrast spatial patterning of microfluidic device wettability
Adam R Abate1, Amber T Krummel, Daeyeon Lee
1School of Engineering and Applied Sciences/Department of Physics, Harvard University, Cambridge, Massachusetts, USA.
Lab on a Chip
|November 22, 2008
Summary
We developed a new photoreactive sol-gel coating for precise control over microfluidic device wettability. This coating allows for high-contrast spatial patterning, essential for advanced microfluidic applications.
Area of Science:
- Materials Science
- Microfluidics Engineering
Background:
- Controlling surface wettability is crucial for microfluidic device functionality.
- Existing methods for wettability control can be complex or lack spatial precision.
Purpose of the Study:
- To introduce a novel photoreactive sol-gel coating for spatial wettability patterning in microfluidics.
- To demonstrate high-contrast patterning capabilities for enhanced microfluidic device design.
Main Methods:
- Development of a photoreactive sol-gel coating formulation.
- Application of photolithography techniques for spatial patterning.
- Characterization of wettability changes on patterned surfaces.
Main Results:
- The sol-gel coating exhibits photoreactivity, enabling selective modification of surface wettability.
- High-contrast patterns in wettability were achieved across the microfluidic device surface.
- The patterned wettability is stable and suitable for microfluidic operations.
Conclusions:
- The photoreactive sol-gel coating offers a versatile and effective method for spatially controlling microfluidic device wettability.
- This technique facilitates the fabrication of sophisticated microfluidic devices with tailored surface properties.

