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Cardiopulmonary function during long-term central venous catheterization
H O'Brodovich1, M Adams, G Coates
1Department of Pediatrics, McMaster University Health Sciences Centre, Hamilton, Ontario, Canada.
The American Journal of Pediatric Hematology/Oncology
|January 1, 1991
Summary
Long-term central venous catheters are safe for ambulatory pediatric cancer patients, showing no significant cardiopulmonary complications. Autopsy reviews revealed minimal issues, supporting safe, extended use for venous access in neoplastic disorders.
Area of Science:
- Pediatric Oncology
- Cardiopulmonary Medicine
- Medical Devices
Background:
- Central venous catheters (CVCs) are crucial for long-term venous access in pediatric patients with neoplastic disorders.
- Concerns exist regarding potential cardiopulmonary complications associated with long-term CVC use.
Purpose of the Study:
- To determine the prevalence of significant cardiopulmonary complications in ambulatory pediatric patients with neoplastic disorders undergoing long-term central venous catheterization.
Main Methods:
- Prospective evaluation of 20 pediatric patients with CVCs for a mean of 13.5 months.
- Utilized pulmonary function testing, chest radiography, V/Q lung scintigraphy, ECG, and echocardiography.
- Retrospective review of autopsy reports for 15 patients with CVCs.
Main Results:
- No significant cardiopulmonary complications were observed in the prospective cohort.
- No evidence of thrombus formation, pulmonary emboli, or pulmonary hypertension.
- Autopsy review showed rare superficial endocardial reactions and mural thrombi, with no direct correlation to catheter removal.
Conclusions:
- Long-term central venous catheters can be safely utilized in ambulatory pediatric patients with neoplastic disorders.
- The study supports the safety and efficacy of CVCs for extended venous access in this population.