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Updated: Jun 27, 2026

Chemoselective Preparation of 1-Iodoalkynes, 1,2-Diiodoalkenes, and 1,1,2-Triiodoalkenes Based on the Oxidative Iodination of Terminal Alkynes
09:54

Chemoselective Preparation of 1-Iodoalkynes, 1,2-Diiodoalkenes, and 1,1,2-Triiodoalkenes Based on the Oxidative Iodination of Terminal Alkynes

Published on: September 12, 2018

Enantioselective iridium-catalyzed allylic arylation

Damien Polet1, Xavier Rathgeb, Caroline A Falciola

  • 1Department of Organic Chemistry, University of Geneva, 30 quai Ernest Ansermet, 1211 Genève 4, Switzerland.

Chemistry (Weinheim an Der Bergstrasse, Germany)
|December 17, 2008
PubMed
Summary

This study introduces the first iridium-catalyzed allylic substitution using arylzinc reagents, achieving high enantioselectivity. The method is versatile, enabling the synthesis of complex molecules like (+)-sertraline.

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