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Updated: Jun 26, 2026
Transplantation of Olfactory Ensheathing Cells to Evaluate Functional Recovery after Peripheral Nerve Injury
Published on: February 23, 2014
Polyethylene glycol-conjugated immunoliposomes specific for olfactory ensheathing glial cells
V P Chekhonin1, O I Gurina, O V Ykhova
1Laboratory of Immunochemistry, V. P. Serbskii State Research Center of Social and Forensic Psychiatry, Russian Ministry of Health, Russia. tsibylkina@gmail.com
Abstract:
A novel immunoliposome delivery system was developed for directed transport into cultured olfactory epithelium cells. Monoclonal antibodies against glial fibrillary acidic protein (GFAP) served as a vector. Fluorescence microscopy showed that the target cells are specifically stained with Dil dye incorporated into liposomal membranes. This transport system holds promise for the delivery of bioactive substances to olfactory epithelial cells and modulation of their capacity to stimulate axonal regeneration.
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