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Updated: Jun 26, 2026
12:03
Antimicrobial Synergy Testing by the Inkjet Printer-assisted Automated Checkerboard Array and the Manual Time-kill Method
Published on: April 18, 2019
The detection of synergy between meropenem and polymyxin B against meropenem-resistant Acinetobacter baumannii using
George A Pankey1, Deborah S Ashcraft
1Infectious Disease Research, Ochsner Clinic Foundation, New Orleans, LA 70121, USA. gpankey@ochsner.org
Diagnostic Microbiology and Infectious Disease
|January 20, 2009
Abstract:
Time-kill assay and Etest testing for synergy of meropenem (MER) (1x MIC) plus polymyxin B (1/4, 1/2, and 1x MIC) were performed against 8 genetically unique MER-resistant clinical Acinetobacter baumannii isolates. Time-kill assay demonstrated synergy for all isolates, whereas Etest showed synergy in 5 isolates and indifference in 3.
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