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Tilted disc syndrome: an OCT and mfERG study
Marilita M Moschos1, Aristides Triglianos, Tryfon Rotsos
1Department of Ophthalmology, University of Athens, Piraeus, Greece. moschosmarilita@yahoo.fr
Documenta Ophthalmologica. Advances in Ophthalmology
|January 24, 2009
Summary
Tilted disc syndrome can cause retinal nerve fiber layer thinning and reduced macular function, detectable by optical coherence tomography (OCT) and multifocal electroretinogram (mfERG), even without apparent vision loss.
Area of Science:
- Ophthalmology
- Neuro-ophthalmology
- Retinal Imaging
Background:
- Tilted disc syndrome is a congenital anomaly of the optic nerve head.
- Assessing its impact on retinal structure and function is crucial for early detection of potential visual impairment.
Purpose of the Study:
- To evaluate retinal thickness and function in tilted disc syndrome using optical coherence tomography (OCT) and multifocal electroretinogram (mfERG).
Main Methods:
- Studied 21 eyes with tilted discs and 20 control eyes.
- Utilized OCT3 to measure foveal and retinal nerve fiber layer (RNFL) thickness.
- Employed mfERG to assess macular cone function.
Main Results:
- Eyes with tilted discs showed significantly decreased superior RNFL thickness (106.47 ± 24.1 µm).
- Macular cone function was significantly reduced in both foveal (11.75 nV/deg²) and parafoveal (8.22 nV/deg²) areas compared to controls.
Conclusions:
- OCT and mfERG are objective tools for detecting anatomical and functional macular damage in tilted disc syndrome.
- Subtle optic nerve and macular dysfunction may exist in tilted disc syndrome, even without overt visual impairment.
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