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Updated: Jun 26, 2026

Biomolecular Imaging of Cellular Uptake of Nanoparticles using Multimodal Nonlinear Optical Microscopy
Published on: May 16, 2022
Multifunctional nanostructured materials for multimodal imaging, and simultaneous imaging and therapy.
Jaeyun Kim1, Yuanzhe Piao, Taeghwan Hyeon
1National Creative Research Initiative Center for Oxide Nanocrystalline Materials and School of Chemical and Biological Engineering, Seoul National University, Seoul 151-744, South Korea.
Nanotechnology enables advanced biomedical tools. Multifunctional nanoplatforms combine unique properties for targeted imaging, diagnosis, and therapy, advancing nanomedicine.
Area of Science:
- Biomedical Engineering
- Materials Science
- Nanotechnology
Background:
- Nanostructured materials possess unique properties like superparamagnetism and fluorescence.
- Their small size is comparable to biomolecules, making them suitable for biomedical applications.
Purpose of the Study:
- To review fabrication strategies for multifunctional nanoplatforms.
- To summarize applications in targeted multimodal imaging and simultaneous diagnosis and therapy.
Main Methods:
- Fabrication of multifunctional nanoplatforms by combining various nanostructured materials.
- Conjugation of targeting moieties onto nanomaterial surfaces.
Main Results:
- Multifunctional nanoplatforms enable synergetic effects for advanced applications.
- Targeted moieties provide specificity for imaging and therapy.
Conclusions:
- Nanotechnology is crucial for future biomedical advancements.
- Multifunctional nanoplatforms offer promising solutions for integrated medical solutions.
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