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Updated: Jun 26, 2026
08:42
A Novel Human Epithelial Enteroid Model of Necrotizing Enterocolitis
Published on: April 10, 2019
[Necroticing fasciitis in children]
Karsten Gjessing Jensen1, Kim Kristensen
1Rigshospitalet, Paediatrisk afdeling. drgjessing@gmail.com
Ugeskrift for Laeger
|January 29, 2009
Summary
Necrotizing fasciitis (NF) rarely affects children but can occur after procedures or from skin infections. Prompt treatment including antibiotics and surgery can lead to survival in pediatric cases.
Area of Science:
- Pediatric Infectious Diseases
- Surgical Infections
Background:
- Necrotizing fasciitis (NF) is a severe soft tissue infection characterized by rapid necrosis of the fascia.
- While rare in children, NF poses a significant threat due to its aggressive progression.
Observation:
- This report details two pediatric cases of necrotizing fasciitis.
- One case originated post-joint puncture, the other following lymph node extirpation.
- Unlike adults, these children lacked significant underlying chronic illnesses.
Findings:
- Both pediatric patients received a multi-modal treatment approach: antibiotics, human immunoglobulin, hyperbaric oxygen, and repeated surgical interventions.
- Successful outcomes were achieved, with both patients surviving the infection.
Implications:
- The findings highlight that children with NF may not present with comorbidities common in adult cases.
- Varicella zoster ulcers are identified as a frequent entry point for infection in pediatric NF.
- Aggressive, comprehensive treatment strategies are crucial for managing pediatric necrotizing fasciitis.
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