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Updated: Jun 26, 2026

Therapy Testing in a Spheroid-based 3D Cell Culture Model for Head and Neck Squamous Cell Carcinoma
Published on: April 20, 2018
Multimodal treatment for head and neck cancer
1Department of Surgical Oncology, Fox Chase Cancer Center, 333 Cottman Avenue, Philadelphia, PA 19011, USA. miriam.lango@fccc.edu
Abstract:
Head and neck cancers are relatively less common tumors, but with complex anatomic and physiologic relationships to the structures from which they arise. Multimodal management is required for advanced stage disease, while single modality treatment is usually sufficient for early lesions. Treatment paradigms have shifted toward more functional preservation of speech and swallowing, when possible. Increased use of radiation, systemic/targeted therapies and function-preserving surgical approaches have allowed for organ preservation without compromising oncologic outcomes in properly selected patients.
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