Related Experiment Video
Updated: Jun 26, 2026

Robotic Duodenal Sleeve Resection for Gastrointestinal Stromal Tumor with Rare Exon 8 KIT Mutation Following Neoadjuvant Imatinib
Published on: April 3, 2026
Multidisciplinary treatment of gastrointestinal stromal tumors
T Peter Kingham1, Ronald P DeMatteo
1Department of Surgery, Memorial Sloan-Kettering Cancer Center, 303 E. 60th Street, Apt 28E, NY, NY 10022, USA. kinghamt@mskcc.org
Abstract:
Gastrointestinal stromal tumor (GIST) has been recognized as a unique tumor only in the last decade. Although rare as a clinical entity, there is much interest in the pathology and treatment because the KIT protooncogene mutation common to most GISTs can be inhibited by imatinib mesylate. Diagnosing and treating GIST requires a multidisciplinary approach, given the combination of pathologic and radiographic evaluation, surgical treatment, and oncologic care required to successfully treat patients with GIST.
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